Research Projects


Next Generation Sequencing and big data analysis of calcium remodeling in colorectal cancer  (2016-2018).
Funded with 60.000 € by the Spanish Association against cancer (AECC) to support a fellowship for Enrique Perez-Riesgo. PI. Carlos Villalobos

 

Calcium remodeling in aging and cancer (2016-2018) Ref. BFU2015-70131-R
Funded with 169.400 € by the Ministry of Economy and Competitivity of Spain. PI. Carlos Villalobos

 

Modulation of mitocondrial calcium as neuroprotection mechanism in brain damage models (2014-2016). Ref VA145U13.
Funded with 33.000 € by Regional Government of Castilla y León, Spain. PI. Lucía Núñez. 

 

Chemoprevention of colorectal cancer by polyamine synthesis inhibitors (2014). Ref. BIO/VA46/14
Funded with 13.865 € by Regional Government of Castilla y León, Spain. PI. Carlos Villalobos

 

Inflammatory mediators and intracellular calcium in Alzheimer´s disease (2013). Ref BIO/VA33/13.
Funded with 7.925 € by Regional Government of Castilla y León, Spain. PI. Lucía Núñez

 

Molecular basis of amyloid toxicity in Alzheimer´s disease (2011-2012). Ref. BIO103/VA45/11
Funded with 21.063 € by Regional Government of Castilla y León, Spain. PI. Carlos Villalobos

 

Remodeling of subcellular calcium homeostasis as basis for proliferation and apoptosis resistance of tumor cells (2010-2013). Ref.  BFU2009-08967.
Funded with 266.200 € by Ministry of Science and Innovation of Spain. PI. Carlos Villalobos

 

Role of cytosolic free calcium in cell responses to Aplidin and PM02734 (2009-2011).
Funded with 22.000 € by PharmaMar SA (Madrid, Spain). PI. Lucía Núñez.

 

Neuroprotection in Alzheimer´s disease based in antagonists of cell and mitocondrial calcium (2009-2010).
Funded with 28.650 € by Regional Government of Castilla y León, Spain. PI. Lucía Núñez. 

 

Control of cell proliferation by calcium signals in colorectal cancer cells: role of mitocondria and Stimand Orai proteins (2008-2010). Ref. Ref. CSI12A08.
Funded with 12.900 € by Regional Government of Castilla y León, Spain. PI. Carlos Villalobos

 

The calcium hypothesis of Alzheimer´s disease: role of mitocondrial calcium in neuron damage and neuroprotection by NSAIDs (2008-2010). Ref. PI07/0766.
Funded with 118.580 € by Instituto de Salud Carlos III, Spain. PI. Lucía Núñez.

 

Use of cementoblasts for periodontal cell therapy (2007-2008)
Funded with 60.000 € by the Regional Federation of Saving Banks of Castilla y León, Spain. PI. Carlos Villalobos.

 

Role of mitochondria and subcellular calcium in the control of cell proliferation: pharmacologic implications (2006-2009). Ref. BFU2006-05202.
Funded with 163.350 € by Ministry of Education and Science, Spain. PI Carlos Villalobos.